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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UHRF1 All Species: 11.82
Human Site: S709 Identified Species: 26
UniProt: Q96T88 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T88 NP_001041666.1 793 89814 S709 K D R P A S G S P F Q L F L S
Chimpanzee Pan troglodytes XP_001139655 792 89650 S708 K D R P A S G S P F Q L F L S
Rhesus Macaque Macaca mulatta XP_001082893 795 89906 S711 K D R P A S G S P F Q L F L S
Dog Lupus familis XP_868468 799 89797 R715 K D G P G S A R P F Q K F L S
Cat Felis silvestris
Mouse Mus musculus Q8VDF2 782 88285 G698 V L T S L Q D G P Y Q I F L S
Rat Rattus norvegicus Q7TPK1 774 87430 G690 V L S S L Q D G P Y Q I F L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507628 851 95788 K767 D E V L A S L K E G P N F L K
Chicken Gallus gallus XP_418269 760 84868 K676 N E V L D A L K D G P K F L N
Frog Xenopus laevis NP_001129236 772 86955 K688 S E V M L F L K E G P K F V N
Zebra Danio Brachydanio rerio NP_998242 775 87072 S690 D E A M E S L S L G P R F V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791602 653 73619 S570 S I I E E C N S G K K F I T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.2 88.1 N.A. 74.9 75.7 N.A. 53.3 71.5 66.5 68 N.A. N.A. N.A. N.A. 47.5
Protein Similarity: 100 99.7 98.8 92.7 N.A. 87 87.5 N.A. 68.5 82 79.9 83 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 100 100 66.6 N.A. 33.3 33.3 N.A. 26.6 13.3 6.6 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 66.6 N.A. 46.6 46.6 N.A. 33.3 33.3 26.6 40 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 37 10 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 37 0 0 10 0 19 0 10 0 0 0 0 0 0 % D
% Glu: 0 37 0 10 19 0 0 0 19 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 37 0 10 91 0 0 % F
% Gly: 0 0 10 0 10 0 28 19 10 37 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 0 0 0 0 0 0 19 10 0 0 % I
% Lys: 37 0 0 0 0 0 0 28 0 10 10 28 0 0 10 % K
% Leu: 0 19 0 19 28 0 37 0 10 0 0 28 0 73 0 % L
% Met: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 10 0 0 28 % N
% Pro: 0 0 0 37 0 0 0 0 55 0 37 0 0 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 0 0 55 0 0 0 0 % Q
% Arg: 0 0 28 0 0 0 0 10 0 0 0 10 0 0 0 % R
% Ser: 19 0 10 19 0 55 0 46 0 0 0 0 0 0 55 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 19 0 28 0 0 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _